Esophageal Myotomy

Indications


Esophageal myotomy is primarily indicated for:

  • Achalasia:
    • Most common indication
    • Effective for Type I, II, and III achalasia
    • Relieves failure of LES relaxation

Other indications include:

  • Spastic Motility Disorders:
    • Diffuse Esophageal Spasm (DES)
    • Jackhammer Esophagus (Hypercontractile)
    • Nutcracker Esophagus (less commonly)
    • Considered when symptoms are severe and unresponsive to medication
    • May require longer myotomy
  • Esophagogastric Junction Outflow Obstruction (EGJOO):
    • Incomplete LES relaxation without full achalasia
    • Considered when persistent symptoms are present
  • Failed Previous Treatments:
    • Rescue therapy after pneumatic dilation, botulinum toxin injection, or previous myotomy
  • Esophageal Leiomyoma:
    • Myotomy for enucleation of benign smooth muscle tumors
  • Epiphrenic Diverticula:
    • Associated with motility disorder and LES dysfunction
    • Myotomy is done alongside diverticulectomy

Contraindications:

  • Absolute:
    • Severe erosive esophagitis
    • Coagulopathy
    • Portal hypertension with cirrhosis
    • Esophageal malignancy at target site
    • Extensive submucosal fibrosis
    • General anesthesia intolerance
  • Relative:
    • Severe stasis esophagitis
    • Esophageal candidiasis
    • End-stage sigmoid esophagus (may require esophagectomy)

Preparation


Preoperative Workup:

  • High-Resolution Manometry (HRM):
    • Gold standard for diagnosis
    • Determines LES relaxation and esophageal peristalsis
  • Barium Swallow:
    • Assesses anatomy, dilation, emptying, tortuosity, and diverticula
  • Upper Endoscopy (EGD):
    • Rules out pseudoachalasia, esophagitis, malignancy, food stasis
  • Chest CT (if needed):
    • Used for large diverticula, tumors, or megaesophagus

Diet and Fasting:

  • Clear liquids for 1–3 days pre-op
  • NPO 8–12 hours before procedure
  • In achalasia with retention, pre-endoscopy for lavage may be done

Medication Review:

  • Discontinue anticoagulants and antiplatelets per protocol
  • Adjust medications for hypertension, seizures, diabetes

Other Measures:

  • Anesthesia evaluation
  • Blood tests, ECG, chest X-ray
  • Pulmonary function tests (if thoracic approach planned)
  • Treat active esophagitis or candidiasis
  • Smoking cessation
  • Post-op support planning

Patient Positioning


Based on approach:

  • Laparoscopic Heller Myotomy:
    • Supine or modified lithotomy
    • Reverse Trendelenburg
    • Arms at sides or on boards
  • Thoracoscopic Approach:
    • Left thoracoscopy: Right lateral decubitus
    • Right thoracoscopy: Left lateral or prone position
    • Table flexed to widen intercostal spaces
  • POEM (Peroral Endoscopic Myotomy):
    • Supine with or without shoulder elevation
    • Left lateral position possible
    • General anesthesia with endotracheal intubation

All positions require careful padding and stabilization.

Surgical Approach


1. Laparoscopic Heller Myotomy:

  • Most common for achalasia
  • 5 ports placed in upper abdomen
  • Pneumoperitoneum created
  • Liver retracted for hiatus access

2. Thoracoscopic Myotomy:

  • Ports in chest; lung deflated
  • Used for longer or proximal myotomy
  • Right side preferred for upper/mid esophagus
  • Less common than laparoscopy

3. POEM:

  • Endoscopic, incisionless
  • Mucosal incision and submucosal tunnel
  • Myotomy through tunnel into stomach
  • Mucosal entry closed with clips

Choice depends on disease, anatomy, previous surgeries, and operator expertise.

Intraoperative Steps


Laparoscopic Heller Myotomy

  • Ports placed, liver retracted
  • Dissection of GEJ and hiatus
  • Myotomy: 5–7 cm above GEJ + 1.5–3 cm into cardia
  • Mucosa inspected (air/dye leak test)
  • Repair any perforation
  • Partial fundoplication performed (see below)

Thoracoscopic Myotomy

  • Ports placed; single-lung ventilation
  • Mobilize esophagus, preserve vagus nerves
  • Longitudinal myotomy done
  • Mucosal integrity checked
  • Antireflux procedure optional/difficult
  • Chest tube placed; lung re-inflated

POEM

  • Mucosal incision (~10–15 cm above GEJ)
  • Submucosal tunnel created to stomach
  • Circular muscle fibers incised
  • Closure of mucosal entry with clips
  • Leak check via contrast swallow

Length and depth of myotomy adjusted to disorder type.

Reconstruction


After Heller Myotomy

Fundoplication (antireflux):

  • Dor (anterior, 180–200°):
    • Fundus covers anterior myotomy
    • Sutured to esophageal muscle and diaphragm
    • Preferred for mucosal protection and reflux control
  • Toupet (posterior, 270°):
    • Fundus wraps behind esophagus
    • More extensive, may risk dysphagia
  • Nissen (360°):
    • Avoided due to high dysphagia risk

After POEM

  • No standard fundoplication
  • Higher GERD risk post-POEM
  • Managed with PPIs
  • Endoscopic reflux procedures under study

Goal: Prevent GERD while avoiding postoperative dysphagia.

Possible Complications and Management


General:

  • Bleeding: Controlled intraoperatively; transfusion rarely needed
  • Infection: Pneumonia, wound infection, mediastinitis
  • Anesthesia risks

Heller Myotomy Specific:

  • Mucosal Perforation: Most common; repaired and covered with fundoplication
  • Pneumothorax (laparoscopic): Requires decompression
  • Organ Injury: Spleen, vagus nerve, lung
  • Port Site Hernia, Adhesions
  • Chronic pain (thoracotomy)

POEM Specific:

  • Gas-related events: Subcutaneous emphysema, pneumoperitoneum—usually self-limiting
  • Mucosal injury or leak: Clipped endoscopically
  • Submucosal bleeding: Managed endoscopically
  • Esophagitis, pleural effusion

Late Complications:

  • GERD:
    • Common after POEM (20–50%), less after Heller with fundoplication
    • Treated with PPIs
  • Recurrent Dysphagia:
    • From incomplete myotomy, fibrosis, tight wrap
    • Managed by dilation, repeat myotomy, botox, or esophagectomy
  • Barrett’s or Cancer:
    • Surveillance recommended

Long-Term Care:

  • Follow-up for symptom monitoring
  • Diet modification
  • Endoscopic surveillance in high-risk cases
×
Popup image