Indications
Esophageal myotomy is primarily indicated for:
- Achalasia:
- Most common indication
- Effective for Type I, II, and III achalasia
- Relieves failure of LES relaxation
Other indications include:
- Spastic Motility Disorders:
- Diffuse Esophageal Spasm (DES)
- Jackhammer Esophagus (Hypercontractile)
- Nutcracker Esophagus (less commonly)
- Considered when symptoms are severe and unresponsive to medication
- May require longer myotomy
- Esophagogastric Junction Outflow Obstruction (EGJOO):
- Incomplete LES relaxation without full achalasia
- Considered when persistent symptoms are present
- Failed Previous Treatments:
- Rescue therapy after pneumatic dilation, botulinum toxin injection, or previous myotomy
- Esophageal Leiomyoma:
- Myotomy for enucleation of benign smooth muscle tumors
- Epiphrenic Diverticula:
- Associated with motility disorder and LES dysfunction
- Myotomy is done alongside diverticulectomy
Contraindications:
- Absolute:
- Severe erosive esophagitis
- Coagulopathy
- Portal hypertension with cirrhosis
- Esophageal malignancy at target site
- Extensive submucosal fibrosis
- General anesthesia intolerance
- Relative:
- Severe stasis esophagitis
- Esophageal candidiasis
- End-stage sigmoid esophagus (may require esophagectomy)
Preparation
Preoperative Workup:
- High-Resolution Manometry (HRM):
- Gold standard for diagnosis
- Determines LES relaxation and esophageal peristalsis
- Barium Swallow:
- Assesses anatomy, dilation, emptying, tortuosity, and diverticula
- Upper Endoscopy (EGD):
- Rules out pseudoachalasia, esophagitis, malignancy, food stasis
- Chest CT (if needed):
- Used for large diverticula, tumors, or megaesophagus
Diet and Fasting:
- Clear liquids for 1–3 days pre-op
- NPO 8–12 hours before procedure
- In achalasia with retention, pre-endoscopy for lavage may be done
Medication Review:
- Discontinue anticoagulants and antiplatelets per protocol
- Adjust medications for hypertension, seizures, diabetes
Other Measures:
- Anesthesia evaluation
- Blood tests, ECG, chest X-ray
- Pulmonary function tests (if thoracic approach planned)
- Treat active esophagitis or candidiasis
- Smoking cessation
- Post-op support planning
Patient Positioning
Based on approach:
- Laparoscopic Heller Myotomy:
- Supine or modified lithotomy
- Reverse Trendelenburg
- Arms at sides or on boards
- Thoracoscopic Approach:
- Left thoracoscopy: Right lateral decubitus
- Right thoracoscopy: Left lateral or prone position
- Table flexed to widen intercostal spaces
- POEM (Peroral Endoscopic Myotomy):
- Supine with or without shoulder elevation
- Left lateral position possible
- General anesthesia with endotracheal intubation
All positions require careful padding and stabilization.
Surgical Approach
1. Laparoscopic Heller Myotomy:
- Most common for achalasia
- 5 ports placed in upper abdomen
- Pneumoperitoneum created
- Liver retracted for hiatus access
2. Thoracoscopic Myotomy:
- Ports in chest; lung deflated
- Used for longer or proximal myotomy
- Right side preferred for upper/mid esophagus
- Less common than laparoscopy
3. POEM:
- Endoscopic, incisionless
- Mucosal incision and submucosal tunnel
- Myotomy through tunnel into stomach
- Mucosal entry closed with clips
Choice depends on disease, anatomy, previous surgeries, and operator expertise.
Intraoperative Steps
Laparoscopic Heller Myotomy
- Ports placed, liver retracted
- Dissection of GEJ and hiatus
- Myotomy: 5–7 cm above GEJ + 1.5–3 cm into cardia
- Mucosa inspected (air/dye leak test)
- Repair any perforation
- Partial fundoplication performed (see below)
Thoracoscopic Myotomy
- Ports placed; single-lung ventilation
- Mobilize esophagus, preserve vagus nerves
- Longitudinal myotomy done
- Mucosal integrity checked
- Antireflux procedure optional/difficult
- Chest tube placed; lung re-inflated
POEM
- Mucosal incision (~10–15 cm above GEJ)
- Submucosal tunnel created to stomach
- Circular muscle fibers incised
- Closure of mucosal entry with clips
- Leak check via contrast swallow
Length and depth of myotomy adjusted to disorder type.
Reconstruction
After Heller Myotomy
Fundoplication (antireflux):
- Dor (anterior, 180–200°):
- Fundus covers anterior myotomy
- Sutured to esophageal muscle and diaphragm
- Preferred for mucosal protection and reflux control
- Toupet (posterior, 270°):
- Fundus wraps behind esophagus
- More extensive, may risk dysphagia
- Nissen (360°):
- Avoided due to high dysphagia risk
After POEM
- No standard fundoplication
- Higher GERD risk post-POEM
- Managed with PPIs
- Endoscopic reflux procedures under study
Goal: Prevent GERD while avoiding postoperative dysphagia.
Possible Complications and Management
General:
- Bleeding: Controlled intraoperatively; transfusion rarely needed
- Infection: Pneumonia, wound infection, mediastinitis
- Anesthesia risks
Heller Myotomy Specific:
- Mucosal Perforation: Most common; repaired and covered with fundoplication
- Pneumothorax (laparoscopic): Requires decompression
- Organ Injury: Spleen, vagus nerve, lung
- Port Site Hernia, Adhesions
- Chronic pain (thoracotomy)
POEM Specific:
- Gas-related events: Subcutaneous emphysema, pneumoperitoneum—usually self-limiting
- Mucosal injury or leak: Clipped endoscopically
- Submucosal bleeding: Managed endoscopically
- Esophagitis, pleural effusion
Late Complications:
- GERD:
- Common after POEM (20–50%), less after Heller with fundoplication
- Treated with PPIs
- Recurrent Dysphagia:
- From incomplete myotomy, fibrosis, tight wrap
- Managed by dilation, repeat myotomy, botox, or esophagectomy
- Barrett’s or Cancer:
- Surveillance recommended
Long-Term Care:
- Follow-up for symptom monitoring
- Diet modification
- Endoscopic surveillance in high-risk cases
